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“Mount Everest of proteins” used by algae to build toxins

Cosmos Magazine - Sat 10 Aug 24

While studying how marine algae produce their toxins, scientists discovered the largest protein. The protein, named PKZILLA-1, is 25% larger than the previous record holder titin. Titin ...

Largest protein in nature discovered in algae toxin

New Atlas - Fri 9 Aug 24

Scientists have discovered the largest known protein in biology. Given the fun name of PKZILLA-1, the protein was found in algae cells and helps them make toxins that are responsible for mass ...

Largest protein yet discovered builds algal toxins

Phys.org - Thu 8 Aug 24

While seeking to unravel how marine algae create their chemically complex toxins, scientists at UC San Diego's Scripps Institution of Oceanography have discovered the largest protein yet identified ...

Largest protein yet discovered builds algal toxins, ScienceDaily - Fri 9 Aug 24
Largest protein yet discovered builds algal toxins, Scienmag - Thu 8 Aug 24
Largest protein yet discovered builds algal toxins, Eurekalert - Thu 8 Aug 24

PKZILLA proteins smash protein size limits

CandEN - Fri 23 Aug 24

To make a giant molecule, nature devised a similarly giant solution

Scientists Discover Largest Protein Hidden in Toxic Algae

ZME Science - Mon 12 Aug 24

Researchers uncover record-breaking protein, shedding light on harmful algal blooms and potential new medicines.

Giant Enzymes in Tiny Organisms Synthesize Giant Toxins

GEN - Fri 9 Aug 24

Tilting the scales at 4.7 megadaltons and reaching 1 micron in length, the newly discovered algal enzyme PKZILLA-1 is the largest protein ever identified in biology. Indeed, PKZILLA-1 is 25% ...

Fish-Killing Toxin Sets New Record in Just How Big a Protein Can Get

ScienceAlert - Fri 9 Aug 24

They named it after a monster.

Marine algae use massive enzymes of unprecedented size to biosynthesize fish-killing toxins

Scienmag - Thu 8 Aug 24

Marine algae Prymnesium parvum use massive enzymes dubbed PKZILLAs – some of the largest proteins ever to be identified in nature – to make large and complex prymnesin neurotoxins responsible ...

Marine algae use massive enzymes of unprecedented size to biosynthesize fish-killing toxins, Eurekalert - Thu 8 Aug 24